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  /  Coronavirus   /  Updated Immune System Protocol by our Chairman/CEO Al Holbrook

Updated Immune System Protocol by our Chairman/CEO Al Holbrook

An ounce of prevention is worth a pound of cure (Benjamin Franklin)

Believing that the body was wonderfully and fearfully made, we have updated our immune stimulating protocols (attached) originally written-up by Dr. Ana Casas, a consultant and advisor to our Company, to fight infectious diseases including COVID-19 and it’s variants. Dr. Casas is Board Certified in Anti-Aging and Regenerative Medicine with residency training in Internal Medicine. Ana is traditionally trained with specialty training in preventative, longevity, anti-aging and regenerative medicine. She was selected as one of the “leading physicians of the world” by the International Association of Internists (IAI).

Each year 10 million people worldwide develop tuberculosis and 1.6 million die, making it the most common lethal infection. Infectious disease kills 17 million people each year; 30 new infectious diseases have emerged in the last 20 years. Many of these diseases have no treatment, cure or vaccine. 385 million people have Chronic Obstructive Pulmonary Disease (COPD), 3 million die annually making it the third leading cause of death worldwide.

The World Health Organization (WHO) reports that 91% of the world’s population live in places where air quality exceeds WHO guideline limits. Infectious diseases like COVID-19 have been with us, are here to stay and our best offense is a good defense like diet, fresh air, sunlight and nutraceuticals.

We have proven with our Communities that developing buildings with UV lighting in many of the common HVAC systems (can kill the Ebola virus), negative ion emission (lifts moods and kills viruses and bacteria), full building water filtration systems; all make a difference. The attached revised protocol is our third step of several to come to protect you and your loved ones from something which is; frankly part of a viral family that has been a part of the earth’s microbiome for thousands of years.

With Blessings we offer this to you and your loved ones as a phased plan to minimize, if not eliminate, the harmful effects of COVID-19 or any virus in our buildings.

We have many other protocols coming which are part of our “New Awakening with Common Sense”. GodSpeed, Live in no Fear and Cheers!

Al Holbrook MPH
Chairman
Holbrook Life Management, LLC
 

 

Holbrook Optimal Immune System Protocol

Coronaviruses, and especially COVID-19, have become a household word. It is important to have a protocol that optimizes the immune system to reduce the risk of spread of this and all viruses. A virus is not a living thing. It is a code contained in an envelope that has to attach to a cell in order to live and spread.The COVID-19 specifically attaches to the ACE 2 receptor cells in the nose, throat,lungs and other organs throughout the body.

There is a lot that you can do to make your immune system stronger so that ifCOVID-19 or another virus enters your body, you can win the war against the viral invader.
 

 

Symptoms and Clinical Presentations:

COVID-19 SYMPTOMS:

The Centers for Disease Control and Prevention currently lists them as:

  • Fever
  • Cough
  • Shortness of breath or difficulty breathing
  • Chills
  • Repeated shaking with chills
  • Muscle pain
  • Headache
  • Sore throat
  • New loss of taste or smell

Some people may display no symptoms (asymptomatic) yet still be capable ofinfecting others.

The most common way that COVID-19 presents is with fever and dry cough accompanied by flu-like symptoms.

 

 

There are other symptoms that have specifically been observed with COVID-19:

Eye symptoms:

There are reports that some people may experience eye symptoms early on such asconjunctivitis (pink eye) and eye discharge.

Gastrointestinal symptoms:

Some people may experience gastrointestinal symptoms such as loss of appetite ordiarrhea in addition to respiratory symptoms or in place of it.

Loss of Sense of smell and taste:

Another symptom includes loss of sense of smell and taste in people with COVID-19. This can also occur with other viral respiratory diseases such as the commoncold or influenza, but this is much more common in COVID-19 since it affects theolfactory nerve.

Blood Clotting:

People with severe COVID-19 have a significant increase in developing bloodclots and vascular problems throughout the body. The virus causes excessiveclotting in the tiny capillaries in the lungs where gas exchange takes place, andthis makes it hard for the lungs to deliver oxygen to the blood.

Ischemic Strokes:

In younger people with COVID-19 who do not have traditional stroke risk factors,this increase in blood clotting causes an increased incidence of ischemic strokes.Anti-coagulation therapy has become a standard of care for treatment.

Rashes and Chilbains:

Rashes, plaque-like lesions, and painful red or purple lesions on the fingers or toes,called chilblains, are skin manifestations being seen in COVID-19. They mayrepresent inflammatory effects of the SARS-CoV-2 virus, or they may be due tocoagulation and clotting problems that damage the delicate blood vessels supplyingthe skin. Both factors may cause this wide variety of skin manifestations beingreported in COVID-19 patients.

Older people and people who have pre-existing conditions such as obesity, cancer,auto immune diseases, Type 2 Diabetes or hypertension, have an increased risk forgetting COVID-19. They can have a fast progression to acute respiratory distresssyndrome (ARDS) and death.
 

Routes of Transmission:

There are four possible routes of transmission of COVID-19:
respiratory droplet, contact, aerosol, and oral-fecal.

 

Respiratory droplet:

Respiratory droplets are believed to be one of the most important routes oftransmitting COVID-19. The virus is found in droplets released from the respiratorytract of an infected individual through a sneeze or cough. When these dropletsare inhaled by a person who is close to the infected person then the virus istransmitted. Because respiratory droplets play such an important role in spreadingof the virus, it is crucial that a mask and preferably an N-95 mask be used andsocial distancing of 6 or more feet between individuals be used whenever possible.Respiratory droplets may land on or near another person, be picked on the hands,and transferred to the respiratory tract through touching the nose, mouth, or eyes. Amask also helps to remind an individual not to touch their face. The CDC stated inmid-May 2020 that infection via contaminated surfaces is not likely to be a majorroute of transmission for the virus but it should still be addressed since it ispossible if the respiratory droplets are still present.

Contact:

Direct person-to-person contact is another way that the virus canspread. In this situation, the virus is transferred when a person who does not havethe virus comes into contact with an infected person who is actively sheddingvirus. This is the reason that staying at least 6 feet apart is so important.

Aerosol:

The aerosol route of transmission involves breathing in viral particlesthat are in the air. These can be at a distance from the infected person. Aerosoltransmission appears to be an especially important concern in healthcare settings.SARS-CoV-2 aerosols are detectable for up to three hours in the air. Transmissionof viral particles can increase by a cough, speaking and even breathing.

Oral-fecal:

The oral-fecal route is another way the virus can be spreadthrough the feces. The virus can be found in feces. This is more common in peoplewith diarrhea who are shedding the virus. Surfaces can become contaminated andthen by touching those surfaces the virus can be brought to the face and into therespiratory tract. This is an uncommon but well documented route of transmissionfor coronaviruses such as the SARS virus. It is very important to address this routein order to contain transmission of the virus.

Protective Measures:

Below are some basic measures to consider in order to reduce your risk ofcontracting COVID-19 and other viral illnesses.

Face Masks:

Cloth masks, surgical masks and N95 (to N99) respirator masks are the threeavailable mask choices. Of the three choices, the N95 (to N99) respirator mask hasthe highest chance of preventing the transmission of the virus.The recommendation for widespread cloth face mask use is to help reduce thespread of COVID-19 in the community. Cloth face masks reduce the amount ofvirus than can be spread from an infected person to an uninfected person, but theyoffer very limited protection against infection with SARS-CoV-2. Cloth maskshould not be used as a substitute for social distancing. Cloth masks help preventthe spread of infection by lowering the spread of respiratory droplets into the environmentby someone who is infected with the virus.This is very important becausemany people infected with SARS-CoV-2 show any or just mild symptoms and maynot realize they have it.

An N95 mask has a filtering ability down to, and actually below, the size of SARSCoV- 2, the virus that causes COVID-19. So, the coronavirus is about 0.12 micronsin diameter and N95 masks protect transmission of this size particle for up to 95%of the time. An N99 masks protect transmission of this size particle for up to 99%of the time.Cloth face masks made of high-quality, high-thread-count woven cotton are beingrecommended for the public, but they do not offer the same protection as an N95(to N99) mask. The N95 (to N99) masks are being reserved for healthcare workerswho are at highest risk of receiving and transmitting the virus due to longer hoursof exposure to the virus and higher risk of exposure due to their work environment.

Social distancing:

The most effective strategy to protect yourself from COVID-19 is to avoid cominginto contact with a person who has the virus. Since the virus is found throughoutthe world and is so widespread, you should assume the people you come in contactwith may be infected and stay at least six feet away from them. A person can beinfected and shed the virus for several days before they have symptoms and inasymptomatic carriers of the virus, they may never experience symptoms at all.

The Centers for Disease Control and Prevention (CDC) and other health authoritiesworldwide strongly advise that people who are at increased risk for getting thevirus and who live in communities experiencing community spread of COVID-19,that they avoid situations where groups of 10 or more people gather and maintainat least 6 feet of distance from others when possible.

Avoid non-essential travel:

Avoiding travel to areas with known community spread is recommended. All airtravel should be avoided as it is associated with exposure to people and theinfectious diseases they carry. It is well documented that traveling on commercialairlines increases the risk of transmission of viruses and other infectious diseases.

Outbreaks measles, influenza, SARS, COVID-19 and many other infectiousdiseases aboard commercial flights have been documented. Transmission ofCOVID-19 on mass public transportation such as a bus, have also been documented.Therefore, avoiding air travel or any mass transportation system is a reasonableprecaution for reducing your risk of viral infections and especially if you are athigh risk.

Wash your hands:

COVID- 19 is a virus which is not alive so it basically a code in an envelope thatbreaks down when exposed to soap and water. It destroys it. Frequent hand washingis an important strategy for protecting against all types of infectious diseasesand especially viruses. Disinfectants and hand sanitizers that contain at least 70%alcohol can inactivate the virus on contact and have been shown to be effective inreducing the spread of the virus.

Disinfect surfaces:

It is very important to disinfect high touch surfaces such as doorknobs, telephones,countertops, keyboards, etc., SARS-CoV-2 aerosols have been detected for up tothree hours in the air. The virus was also found on cardboard for up to 24 hours andfor up to three days on plastic and stainless steel. Transmission by contact fromthese surfaces is less likely but still a possibility.

Coronaviruses are not alive, and they are basically a code that can be inactivatedwith proper cleaning and disinfecting agents. Therefore, keeping surfaces clean andproperly disinfected is important to limit the spread of infectious diseases causedby coronaviruses.Regarding which disinfectants are best for inactivating the virus, the United StatesEnvironmental Protection Agency (EPA) provides a list of EPA-registered disinfectantproducts for use against the SARS-CoV-2 (COVID-19) virus. The list isavailable on the EPA’s web page: https://www.epa.gov/pesticide-registration/list-n-disinfectants-use-against-sars-cov-2

Strengthen immunity:

Optimal functioning of the immune system is vital for defending against all typesof infections, from mild colds to the seasonal flu all types of pneumonia. Anutrient-dense diet, regular exercise, adequate sleep, and stress management can allcontribute to healthy immune function.

Optimal Nutrition:

Optimal nutrition through the food, drink and supplements that you take is importantfor a well-functioning immune system to protect against viral infections.

Melatonin:

The over the counter hormone, melatonin, is the most important antioxidant thatthe body makes. As we get older, the melatonin level decreases. It is a veryimportant anti-inflammatory hormone and a regulator of the immune system.There is evidence that melatonin may reduce the severity of the disease.Melatonin is effective in patients who are critically ill by acting as an anti-inflammatory,reducing anxiety and improving sedation and sleep quality, which mightalso be beneficial for better clinical outcomes for COVID-19 patients.There is significant data showing that melatonin limits virus-related diseases andwould also likely be beneficial in COVID-19 patients.

Melatonin has a high safety profile.The recommended dose of melatonin is between 0.5 mg- 3 mg orally nightly atbedtime. Once it has been taken, it is important to avoid looking at any type oflight source that would decrease the melatonin level.

Vitamin D:

Vitamin D is an important hormone that helps to regulate the immune system. It is so important that it is the only hormone that our skin can make through exposure to the sun. Many people have a low Vitamin D level that increases their risk of getting a viral illness or many other types of diseases. People with the lowest Vitamin D levels (levels less than 15 ng/mL) were 2.6 times more likely to develop pneumonia compared with those with the highest vitamin D levels in a study that followed older people for nearly 10 years.

Vitamin D deficiency may increase the risk of death in hospitalized patients with community-acquired pneumonia. Medical research shows a clear correlation between a low Vitamin D level and a higher risk of dying from COVID-19. Vitamin D has the ability to increase antimicrobial immune activity. Also, vitamin D deficiency is associated with fewer immune cells in the blood, increasing susceptibility to infection.

Vitamin D is also an immune modulator, involved in stimulating innate immune activity and regulating tissue-damaging inflammation. Vitamin D level can be checked with a blood test called 25 Hydroxy Vitamin D level and the level should be between 50-80 ng/mL for it to be optimal. Vitamin D is stored in the liver and can be toxic if the level is greater than 100 ng/mL so proper lab monitoring is important when taking this as a supplement.
Vitamin D absorption can be increased by taking it at the same time as Omega 3 fish oil or any other type of oil.

Vitamin C:

Vitamin C is an antioxidant and anti-inflammatory which plays an important rolein having an optimal immune system.Vitamin C may help treat COVID-19 patients, but it is being studied in intravenousform and not as an oral dose.There is no evidence that taking vitamin C will help prevent infection with thecoronavirus that causes COVID-19 but it can be taken as a supplement to optimizethe immune system function.The recommended dose of Vitamin C for optimizing the immune system is500 to 1000 mg orally daily.

Elderberry (Sambucol®):

Elderberry has a potent direct antiviral effect against the flu virus.It is believed to be beneficial for the prevention and treatment of influenza andupper respiratory infections.It inhibits the early stages of an infection by blocking key viral proteins responsiblefor both the viral attachment and entry into the host cells.Even though elderberry was shown to have inhibit all stages of flu virus infection,it had a significantly stronger effect on the late stage of infection than at earlystage.

Elderberry has been shown to be effective against 10 strains of influenza virus and its effectiveness compares favorably to the known anti-influenza activities ofoseltamivir (Tamiflu) and amantadine.

The recommended form of Elderberry is Sambucol® which was used in the fluvirus clinical trials.Elderberry has not been studied in COVID-19 patients, but it has been found to bebeneficial in the treatment and prevention of the seasonal flu virus and in optimizingthe immune system.The dose For Daily Maintenance of the Immune System:

  • Adults and Children over 4 Years: 2 teaspoons (10ml) daily
  • For Intensive Use
  • Adults and Children over 4 Years: 2 teaspoons (10ml) 4 times daily

Lactoferrin and Colostrum:

Lactoferrin is a glycoprotein found in colostrum which is the first milk producedby human and cow milk. It plays an important role in the immune system function.Lactoferrin boosts the immune system through its antibacterial, antiviral, and antifungalproperties.It acts as an antiviral by activating the antiviral cytokines interferon (IFN)-α/β andboosting natural killer (NK) cell activity and Th1 cytokine responses. There arestudies that show that lactoferrin may lower the incidence and severity of commonrespiratory tract viral infections, like colds and flu.During the SARS epidemic that emerged in 2003, researchers reported in 2005 thatthe gene encoding lactoferrin was highly upregulated in patients that had the viruswhich they concluded that it plays a role in the innate immune response to the infection.A follow-up study suggested that lactoferrin interfered with the ability ofthe 2003 SARS virus from interrupting the functional and structural integrity ofhost cells.

Lactoferrin (apolactoferrin) dose: 250 mg to 300 mg daily.

Zinc:

Zinc plays an important role in the immune system. Zinc is necessary for immunecell development and communication and plays an important role in lowering inflammation.Nursing home residents with lower zinc status had almost twice therisk of pneumonia as those with normal zinc status in a yearlong medical study.Low levels of zinc can lower the immune system function, increase the length oftime and incidence of pneumonia and prolong recovery from bacterial and viralillnesses. In the elderly, low zinc levels are associated with an increased rate ofdeath from all causes. Zinc is necessary for normal cell division and developmentas, so it is really important for the immune cells to be able to divide and multiplyproperly.Zinc supplements may lower the length of time and the severity of upper respiratorytract infections. Zinc also plays a role in prevention of upper respiratory infections.A randomized controlled clinical trial in adults aged 55–87 found daily supplementationwith 45 mg zinc gluconate for 12 months was associated with lowerincidence of infections compared with placebo.Covid-19 causes bilateral pneumonia. Because pneumonia can be a complicationof an upper respiratory tract infection preventing colds or reducing their severitymay help protect against pneumonia and the severity of infection from a viralillness like Covid-19.

  • Recommended dose: Opti-Zinc® Zinc monomethionine 30 mg daily
  • Opti-Zinc® also has an added dose of copper 300 mcg per daily dose
  • which can become depleted when taking zinc long term.

Selenium:

Selenium has important antioxidant, anti-inflammatory, and antiviral activities in the body, and deficiency is associated with increased risk of viral infection. There have been links between selenium levels in the body and cure or death rates of those with the COVID-19 virus. The more optimal the selenium level in the patient, the higher the cure rate from Covid-19.
Recommended dose:

  • 200 mcg daily of selenium (as selenomethionine)

 

Probiotics:

Probiotics are good bacteria like Bifidobacterium and Lactobacillus species whichhelp to optimize the immune response. They have been shown to possibly reducethe number, duration and severity of viral respiratory tract infections such as influenza.They have not been studied in the treatment of COVID-19, but they arebelieved to improve immune system function.One randomized controlled trial with over 700 healthy volunteers showed a preparationcontaining probiotics (Lactobacillus plantarum, Lactobacillus rhamnosus,and Bifidobacterium lactis), lactoferrin, and prebiotics (non-digestible fibers thatcan serve as a food source for beneficial gut bacteria) lowered the incidence ofrespiratory diseases during the cold season.Combining probiotics with lactoferrin and prebiotics was shown to decrease thenumber, severity, and duration of upper respiratory infections and an added benefitwas that there was an improvement in bowel function.The same probiotic blend, given with colostrum, the first milk produced by thecow, lowered the incidence of flu compared with vaccination and with no treatment.Bacillus subtilis CU1 is another probiotic that enhanced the immune response andreduced the frequency of respiratory infections in elderly research participants.
Recommended dose:

  • Garden of Life Dr. Formulated Probiotics Platinum Series Immune+
  • with 90 Billion CFU Guaranteed. One daily.

Peptides:

Thymosin Alpha 1:

Thymosin Alpha 1 is a peptide, consisting of amino acids, that significantly reducedmortality of severe COVID-19 patients.It tripled survival in ICU patients that received it.
Journal of Clinical Infectious Disease
Published online May 22, 2020 ahead of print publication.
Thymosin Alpha 1 (Tα1) Reduces the Mortality of Severe COVID-19 by Restorationof Lymphocytopenia and Reversion of Exhausted T Cells
Lymphocytopenia and T cell exhaustion is notable in acute COVID19 patients, especiallyin aged and severe cases. Thymosin alpha 1 (Tα1) had been used in thetreatment of viral infections as an immune response modifier for many years.Thymosin Alpha 1 significantly reduce mortality of severe COVID-19 patients.

Recommended dose:

  • Thymosin Alpha 1 is by prescription and the dose depends on the severity of disease.

Exercise:

There is abundant evidence that participating in regular physical activity optimizesthe immune system. Exercise is believed to have these effects by activatingimmune cells, reducing stress and improving overall health.

Any form of daily exercise for 20-30 minutes, in which heart rate increases and sweat is produced, is beneficial for the immune system function.

 

Note: This information should not be used to replace advice from your doctor or healthcare provider. Every person is an “individual with a unique DNA footprint or metabolism that may not fit the protocols in this summary communication from outside sources. Never delay seeking medical advice because you have read the recommendations in this protocol. You should always investigate on your own and seek medical advice if you decide to change your medical regime or treatment plan. Note, many nutraceuticals can have adverse effects on the effectiveness of pharmaceuticals and/or adverse contraindications. Do not take any over the counter supplements with any pharmaceutical without the express consent of your physician. The information herein is identified to the specific organization which provided such information and should be investigated before any use.

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